News & Updates

Lab announcements, publications, recruitment notices, milestones, and lab-life moments — newest first.

📣 Recruitment · Open
Synthetic biology · Metabolic engineering

We are hiring PhD students

  • Singapore citizens/PRs: apply via AGS.
  • International students: A*STAR has no direct PhD scholarship. Join as an ARAP/SRAP attachment student if already enrolled in a PhD overseas, or apply via NUS, NTU or SIT.
Join the Lab →
Publication
29 Jul 2026 · Review

New review: glycolaldehyde as a synthetic biology hub for sustainable biomanufacturing ↗

Simon and Dr. Seohyoung Kim's new review in Systems Microbiology and Biomanufacturing positions glycolaldehyde as a metabolic hub linking C1 feedstocks, lignocellulose, and plastic waste to central metabolism.

In the News
6 May 2026 · Nature Spotlight

📰 Featured in Nature: Engineering resilient food systems in a warming world ↗

Simon is featured in a Nature Spotlight on synthetic biology and food security, discussing the lab's work engineering microorganisms to produce flavours, fragrances, and antioxidants — and to reduce dependence on petroleum-derived chemicals. Part of Nature Spotlight: Synthetic biology.

Editorial Role
May 2026 · Submission deadline 12 Jan 2027

🧪 Guest Editor — Scientific Reports Collection on Next-Generation Biomanufacturing ↗

Simon joins Dr. Hyun Gi Koh and Dr. Takuya Matsumoto as Guest Editor for a Scientific Reports (Nature Portfolio) Collection on Next‑Generation Biomanufacturing. The Collection welcomes original research on advanced bioproduction, and bioprocessing. Submissions open until 12 January 2027.

Editorial Role
2026 · Food Bioscience (Elsevier)

🥗 Guest Editor — Special Issue on Bio-based Production of Functional Food Ingredients (BPFFI) ↗

Simon is serving as Guest Editor for an Elsevier special issue on the microbial and enzymatic synthesis of functional food ingredients — covering nutraceuticals, flavours, sweeteners, and bioactives produced via fermentation and biocatalysis. We welcome submissions of original research and reviews.

Milestone
14 Apr 2026

🎓 Xiao Hui defends her PhD thesis

Many congratulations to Dr. LIM Xiao Hui on successfully defending her PhD — a hard-earned milestone, and a proud moment for the lab.

Lab Life
2–4 Apr 2026

🎢 Team bonding at LEGOLAND Malaysia

The whole group spent three days at LEGOLAND in Johor Bahru — rides, building competitions, and a chance to recharge together away from the bench.

Publication
2026

New paper in ACS Synthetic Biology: AUCS control system ↗

We report a new arabinose-inducible univariant control system (AUCS) that enables precise, tunable expression for microbial production of proteins, enzymes, and metabolites.

Research Highlight
2024 · A*STAR Research

Sniffing out scalable solutions for aromatic compounds ↗

Our work on engineering E. coli to produce rose-scent monoterpenes geraniol and geranyl acetate at high titer using innovative microaerobic bioprocesses.

Research Highlight
2023 · A*STAR Research

Mushroom blueprint scores biotech breakthroughs ↗

Structural elucidation of fungal terpene synthases opens new avenues for engineering linalool and nerolidol biosynthesis through rational enzyme design.

Research Highlight
2023 · A*STAR Research

Manufacturing nature's sweet smells ↗

High-yield microbial production of trans-nerolidol — a fragrance ingredient widely used in food and cosmetics — achieved from simple sugar and glycerol feedstocks.

Research Highlight
2021 · A*STAR Research

Bacteria turn nature's rainbow into therapeutics ↗

Engineering E. coli to biosynthesize glycosylated carotenoids including zeaxanthin and astaxanthin glucosides with potential nutraceutical and therapeutic applications.